Hotels Near Union Square & East 16th Street Medical Offices

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NYC Hotel & Travel Guide Β· 2026 Edition

Hotels Near Union Square & East 16th Street Medical Offices

Hotels Near Union Square & East 16th Street Medical Offices: addresses, subway lines, walking distance and 2026 NYC nightly rates with tax math.

By Matthew S Crawford Β· Updated October 2026 Β· Verified NYC Rates & Tax Math

Quick answer

Hotels near Union Square medical offices make a convenient choice for visitors with appointments along East 16th Street, Stuyvesant Square and the blocks toward First Avenue. The neighborhood combines subway access, groceries and restaurants with quieter residential streets.

Hotels Near Union Square Medical Offices: East 16th Street and Stuyvesant Square

Hotels near Union Square medical offices make a convenient choice for visitors with appointments along East 16th Street, Stuyvesant Square and the blocks toward First Avenue. The neighborhood combines subway access, groceries and restaurants with quieter residential streets.

Medical services in this part of New York City have changed over time, so confirm which offices, clinics and facilities are operating at your exact address before you book. This guide covers logistics only, offers no medical advice, and claims no hotel partnerships, shuttles or discounts.

Subway Lines and Walking Distance from 14th Street-Union Square

The 14th Street-Union Square station is one of the city’s largest hubs, served by the 4, 5, 6, L, N, Q, R and W trains. From there, the walk east along East 16th Street toward Stuyvesant Square takes about 15 to 20 minutes, by typical estimates. Leave generous time for elevators, street crossings and any security or check-in procedures at the building you are visiting.

The L train also stops at Third Avenue and First Avenue, shortening the east-west leg, and the M14 and M15 buses may help (confirm routes with the MTA). Anyone with limited stamina may prefer a taxi for the final blocks, especially in winter or in heavy rain.

The Midtown skyline at dusk, one subway ride north of Union Square
Photo: Daniel Schwen, CC BY-SA 3.0 / Wikimedia Commons

Union Square and Gramercy Hotel Options Within Walking Distance

Union Square puts you within walking distance of the Greenmarket, bookstores and dozens of casual restaurants. Most hotels here are mid-sized, and the area stays lively into the evening, so request a higher floor if you want to sleep before an early appointment.

Gramercy Park sits just north, and the Gramercy Park Hotel at 2 Lexington Avenue is a well-known address (confirm current status and name). Private park access is typically limited to keyholders, so do not assume guests can use it without asking.

Boutique Hotel Stays in Greenwich Village and the East Village

A short subway ride south opens a wider range of boutique hotel stays. The Washington Square Hotel at 103 Waverly Place and the Bowery Hotel at 335 Bowery are two examples, each with status, room types and rates to confirm directly before you book.

These areas offer excellent food and nightlife, but also late-night noise. Ask for rooms facing away from busy corners, and check the L train, 6 train or bus links that make the trip back to East 16th Street practical after a long day.

Luxury Hotel Choices Farther North in Midtown East and Murray Hill

For a luxury hotel experience, travelers sometimes head north to Midtown East, where the 6 train at 33rd and 42nd Streets provides a direct ride south to Union Square. The Lotte New York Palace at 455 Madison Avenue is one example, with status and amenities to confirm.

Luxury rates generally begin around $650 a night. A $650 room totals $749.38 after the 14.75% tax and the flat $3.50, and a $700 room totals $806.75. Because the ride south adds time, weigh the cost against shorter stays closer to the appointments.

Visitors on the Top of the Rock observation deck looking toward the Empire State Building
Photo: Carol M. Highsmith, Library of Congress, public domain

Mid-Range Rates and Hotel Tax Math for $320 to $480 Rooms

Mid-range rooms in Manhattan generally run $320 to $480 per night as a 2026 planning estimate. A $320 room totals $370.70 after tax and fees, while a $480 room totals $554.30. These are examples, not live prices.

Midtown Manhattan hotels usually cost more than similar rooms in Gramercy or the Flatiron area, so a short ride on the 6 or N/R/W can lower the bill. Confirm the final total with the property and the NYC Department of Finance.

Budget Rooms from $195 to $295 and Where They Appear

Budget rooms in the $195 to $295 range appear in Chelsea, Koreatown and near Penn Station, all reachable by subway. A $250 room totals $290.38 after tax. Rates swing widely by date, so compare several nights before choosing.

The Ace Hotel at 20 West 29th Street is a boutique hotel option in the NoMad area, and the New Yorker at 481 Eighth Avenue is a larger Midtown option, each with current status and rates to confirm. Both require a subway or bus ride to East 16th Street. Comparing weekday and weekend hotel rates across Manhattan and Brooklyn.

Frequently Asked Questions About Hotels Near Union Square Medical Offices

Visitors often ask whether Union Square is a good base for appointments on East 16th Street. For many people it is, thanks to the subway hub, though the walk east can be long, so keep a taxi or bus plan ready.

Others ask if hotels offer medical discounts or shuttles. Some might, but nothing should be assumed. Ask directly, get any answer in writing, and compare it with the public rate before you reserve. A written reply protects you if staff change between booking and arrival.

How far is East 16th Street from Union Square?

Roughly 15 to 20 minutes on foot toward Stuyvesant Square, by typical estimates. Confirm your route and allow extra time if mobility is limited.

Is Gramercy a good alternative to Union Square?

Gramercy is quieter and still on the 6 and L trains, but hotel choices are fewer. Compare rates and room types before deciding.

Are there cheaper stays nearby?

Budget rooms in the $195 to $295 range appear in Chelsea, NoMad and Koreatown, though prices change daily. Compare the all-in total.

Keep reading

Chelsea & Flatiron Guide Β· Hotels Near 14th Street-Union Square Station Β· Hotels Near The Cooper Union at Cooper Square & Astor Place Β· Hotels Near Union Square NYC Β· Ace Hotel New York Β· Where to stay in NYC Β· NYCHotelss 20 Best Picks Β· Cheap hotels in NYC Β· All NYC guides

About the author. Matthew S Crawford grew up on Long Island, in Massapequa and then Deer Park. He runs NYCHotelss, an independent NYC hotel guide. Details change. Check rates, hours and policies before you book.